Reduction of p11 in dorsal raphe nucleus serotonergic neurons mediates depression-like behaviors
Abstract The pathology of depression is related to the imbalance of various neurotransmitters. The dorsal raphe nucleus (DRN), the main brain region producing 5-HT, is crucially involved in the pathophysiology of depression. It contains several neuron types, in which GABAergic neurons are activated...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-11-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-023-02664-3 |