Autoimmune B Cell Repertoire in a Mouse Model of Sjögren’s Syndrome

Autoimmune B Cell Repertoire in a Mouse Model of Sjögren’s Syndrome

In genetically prone individuals, chronic immune activation may lead to expansion of autoreactive lymphocyte clones that can induce organ damage developing autoimmune disorders. Sjögren’s Syndrome (SjS) is a systemic chronic autoimmune disease that primarily affects exocrine glands. Despite the accu...

Full description

Bibliographic Details
Main Authors: Manuel Sáez Moya, Rebeca Gutiérrez-Cózar, Joan Puñet-Ortiz, María Luisa Rodríguez de la Concepción, Julià Blanco, Jorge Carrillo, Pablo Engel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
B cell repertoire
autoantibodies
polyreactive antibodies
Sjögren’s syndrome
monoclonal antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.666545/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.666545/full

Similar Items