Relevance of vitamin D receptor target genes for monitoring the vitamin D responsiveness of primary human cells.

Vitamin D3 has transcriptome- and genome-wide effects and activates, via the binding of its metabolite 1α,25-dihydroxyvitamin D3 to the transcription factor vitamin D receptor (VDR), several hundred target genes. Using samples from a 5-month vitamin D3 intervention study (VitDmet), we recently repor...

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Bibliographic Details
Main Authors: Maja Vukić, Antonio Neme, Sabine Seuter, Noora Saksa, Vanessa D F de Mello, Tarja Nurmi, Matti Uusitupa, Tomi-Pekka Tuomainen, Jyrki K Virtanen, Carsten Carlberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395145?pdf=render