RIG-I Detects mRNA of Intracellular <named-content content-type="genus-species">Salmonella enterica</named-content> Serovar Typhimurium during Bacterial Infection

ABSTRACT The cytoplasmic helicase RIG-I is an established sensor for viral 5′-triphosphorylated RNA species. Recently, RIG-I was also implicated in the detection of intracellular bacteria. However, little is known about the host cell specificity of this process and the bacterial pathogen-associated...

Full description

Bibliographic Details
Main Authors: Mirco Schmolke, Jenish R. Patel, Elisa de Castro, Maria T. Sánchez-Aparicio, Melissa B. Uccellini, Jennifer C. Miller, Balaji Manicassamy, Takashi Satoh, Taro Kawai, Shizuo Akira, Miriam Merad, Adolfo García-Sastre
Format: Article
Language:English
Published: American Society for Microbiology 2014-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01006-14