Selection of metastatic breast cancer cells based on adaptability of their metabolic state.

A small subpopulation of highly adaptable breast cancer cells within a vastly heterogeneous population drives cancer metastasis. Here we describe a function-based strategy for selecting rare cancer cells that are highly adaptable and drive malignancy. Although cancer cells are dependent on certain n...

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Bibliographic Details
Main Authors: Balraj Singh, Karen Tai, Simran Madan, Milan R Raythatha, Amanda M Cady, Megan Braunlin, LaTashia R Irving, Ankur Bajaj, Anthony Lucci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3343010?pdf=render