Increased mutability of Staphylococci in biofilms as a consequence of oxidative stress.

To investigate the development of mutational resistance to antibiotics in staphylococcal biofilms.Mutation frequencies to resistance against mupirocin and rifampicin were determined for planktonic cultures and for biofilms generated using either a novel static biofilm model or by continuous flow. DN...

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Bibliographic Details
Main Authors: Victoria J Ryder, Ian Chopra, Alex J O'Neill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3480535?pdf=render