Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction

<p>Abstract</p> <p>Background</p> <p>Generalized hypoxic pulmonary vasoconstriction (HPV) occurring during exposure to hypoxia is a detrimental process resulting in an increase in lung vascular resistance. Nebulization of sodium nitrite has been shown to inhibit HPV. Th...

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Bibliographic Details
Main Authors: Surber Mark W, Hoglen Niel C, Elliott Garry T, Dahal Bhola K, Schermuly Ralph T, Egemnazarov Bakytbek, Weissmann Norbert, Grimminger Friedrich, Seeger Werner, Ghofrani Hossein A
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/81