Direct intranodal tonsil vaccination with modified vaccinia Ankara vaccine protects macaques from highly pathogenic SIVmac251

Direct intranodal tonsil vaccination with modified vaccinia Ankara vaccine protects macaques from highly pathogenic SIVmac251

Mucosal surfaces are a primary route of HIV entry, yet the compartmentalisation between mucosal and peripheral immune systems remain a challenge for HIV vaccine candidates. Authors utilise a combination of intranodal tonsil MALT and systemic vaccination in the rhesus macaque model to explore immune...

Full description

Bibliographic Details
Main Authors: Jeffy G. Mattathil, Asisa Volz, Olusegun O. Onabajo, Sean Maynard, Sandra L. Bixler, Xiaoying X. Shen, Diego Vargas-Inchaustegui, Marjorie Robert-Guroff, Celia Lebranche, Georgia Tomaras, David Montefiori, Gerd Sutter, Joseph J. Mattapallil
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36907-0

Internet

https://doi.org/10.1038/s41467-023-36907-0

Similar Items