Direct intranodal tonsil vaccination with modified vaccinia Ankara vaccine protects macaques from highly pathogenic SIVmac251
Mucosal surfaces are a primary route of HIV entry, yet the compartmentalisation between mucosal and peripheral immune systems remain a challenge for HIV vaccine candidates. Authors utilise a combination of intranodal tonsil MALT and systemic vaccination in the rhesus macaque model to explore immune...
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Bibliographic Details
| Main Authors: |
Jeffy G. Mattathil,
Asisa Volz,
Olusegun O. Onabajo,
Sean Maynard,
Sandra L. Bixler,
Xiaoying X. Shen,
Diego Vargas-Inchaustegui,
Marjorie Robert-Guroff,
Celia Lebranche,
Georgia Tomaras,
David Montefiori,
Gerd Sutter,
Joseph J. Mattapallil |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2023-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-023-36907-0
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