Loss of Katnal2 leads to ependymal ciliary hyperfunction and autism-related phenotypes in mice.

Loss of Katnal2 leads to ependymal ciliary hyperfunction and autism-related phenotypes in mice.

Autism spectrum disorders (ASD) frequently accompany macrocephaly, which often involves hydrocephalic enlargement of brain ventricles. Katnal2 is a microtubule-regulatory protein strongly linked to ASD, but it remains unclear whether Katnal2 knockout (KO) in mice leads to microtubule- and ASD-relate...

Full description

Bibliographic Details
Main Authors: Ryeonghwa Kang, Kyungdeok Kim, Yewon Jung, Sang-Han Choi, Chanhee Lee, Geun Ho Im, Miram Shin, Kwangmin Ryu, Subin Choi, Esther Yang, Wangyong Shin, Seungjoon Lee, Suho Lee, Zachary Papadopoulos, Ji Hoon Ahn, Gou Young Koh, Jonathan Kipnis, Hyojin Kang, Hyun Kim, Won-Ki Cho, Soochul Park, Seong-Gi Kim, Eunjoon Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-05-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002596&type=printable

Internet

https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002596&type=printable

Similar Items