TARGETS FOR MAJORITY OF DRUGS: G PROTEIN-COUPLED RECEPTORS - THEIR STRUCTURE AND INTERACTIONS WITH BIOLIGANDS
G protein-coupled receptors (GPCRs) are the most frequent targets for many drugs. They form the largest superfamily of integral membrane proteins, of which more than 1000 members have the following common features: (i) All GPCRs form 7 hydrophobic a-helices of length -38A (25 amino acids, 7 turns)...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Gdańsk University of Technology
2021-12-01
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| Series: | TASK Quarterly |
| Subjects: | |
| Online Access: | https://journal.mostwiedzy.pl/TASKQuarterly/article/view/2383 |