Successive Passage In Vitro Led to Lower Virulence and Higher Titer of A Variant Porcine Epidemic Diarrhea Virus

A highly virulent porcine epidemic diarrhea virus (PEDV) appeared in China and spread rapidly to neighbor countries, which have led to great economic losses to the pig industry. In the present study, we isolated a PEDV using Vero cells and serially propagated 100 passages. PEDV SDSX16 was characteri...

Full description

Bibliographic Details
Main Authors: Pengwei Zhao, Song Wang, Zhi Chen, Jiang Yu, Rongzhi Tang, Wenbin Qiu, Lu Zhao, Yueyue Liu, Xiaozhen Guo, Hongbin He, Guanlong Xu, Jinxiang Li, Jiaqiang Wu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/4/391