Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design
Abstract The mechanisms by which antibodies confer protection vary across vaccines, ranging from simple neutralization to functions requiring innate immune recruitment via Fc-dependent mechanisms. The role of adjuvants in shaping the maturation of antibody-effector functions remains under investigat...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-023-00613-1 |