Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design

Abstract The mechanisms by which antibodies confer protection vary across vaccines, ranging from simple neutralization to functions requiring innate immune recruitment via Fc-dependent mechanisms. The role of adjuvants in shaping the maturation of antibody-effector functions remains under investigat...

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Bibliographic Details
Main Authors: Carolin Loos, Margherita Coccia, Arnaud M. Didierlaurent, Ahmed Essaghir, Jonathan K. Fallon, Douglas Lauffenburger, Corinne Luedemann, Ashlin Michell, Robbert van der Most, Alex Lee Zhu, Galit Alter, Wivine Burny
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00613-1