Should prenatal chromosomal microarray analysis be offered for isolated ventricular septal defect? A single-center retrospective study from China

Should prenatal chromosomal microarray analysis be offered for isolated ventricular septal defect? A single-center retrospective study from China

ObjectiveTo evaluate the utility of chromosomal microarray analysis (CMA) in fetuses with isolated ventricular septal defect (VSD) and to explore the favorable factors for predicting spontaneous closure of defects.MethodsThe study included 436 singleton pregnancies seen at a referral prenatal diagno...

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Bibliographic Details
Main Authors: Ken Cheng, Hang Zhou, Fang Fu, Tingying Lei, Fucheng Li, Ruibin Huang, You Wang, Xin Yang, Ru Li, Dongzhi Li, Can Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
isolated fetal ventricular septal defect
chromosomal microarray
copy number variants
prenatal diagnosis
postnatal outcome
spontaneous closure
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.988438/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.988438/full

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