Evaluating the comprehensive diagnosis efficiency of lung cancer, including measurement of SHOX2 and RASSF1A gene methylation

Evaluating the comprehensive diagnosis efficiency of lung cancer, including measurement of SHOX2 and RASSF1A gene methylation

Abstract Methylation of the promoters of SHOX2 and RASSF1A (LungMe®) exhibits promise as a potential molecular biomarker for diagnosing lung cancer. This study sought to assess the aberrant methylation of SHOX2 and RASSF1A in broncho-exfoliated cells (BEC) and compare it with conventional cytology,...

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Bibliographic Details
Main Authors: Jian Liu, Tingting Bian, Bin She, Lei Liu, Hui Sun, Qing Zhang, Jun Zhu, Jianguo Zhang, Yifei Liu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Cancer
Subjects:
Lung cancer
DNA methylation
SHOX2
RASSF1A
Diagnosis
Online Access:https://doi.org/10.1186/s12885-024-12022-1

Internet

https://doi.org/10.1186/s12885-024-12022-1

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