Antibody activities in hyperimmune plasma against the Rhodococcus equi virulence -associated protein A or poly-N-acetyl glucosamine are associated with protection of foals against rhodococcal pneumonia.

The efficacy of transfusion with hyperimmune plasma (HIP) for preventing pneumonia caused by Rhodococcus equi remains ill-defined. Quarter Horse foals at 2 large breeding farms were randomly assigned to be transfused with 2 L of HIP from adult donors hyperimmunized either with R. equi (RE HIP) or a...

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Main Authors: Susanne K Kahn, Colette Cywes-Bentley, Glenn P Blodgett, Nathan M Canaday, Carly E Turner-Garcia, Mariana Vinacur, Sophia C Cortez-Ramirez, Patrick J Sutter, Sarah C Meyer, Angela I Bordin, Daniel R Vlock, Gerald B Pier, Noah D Cohen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0250133