Harnessing the IL-21-BATF Pathway in the CD8<sup>+</sup> T Cell Anti-Tumor Response
In cancer, CD8<sup>+</sup> T cells enter a dysfunctional state which prevents them from effectively targeting and killing tumor cells. Tumor-infiltrating CD8<sup>+</sup> T cells consist of a heterogeneous population of memory-like progenitor, effector, and terminally exhauste...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-03-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/6/1263 |