Harnessing the IL-21-BATF Pathway in the CD8<sup>+</sup> T Cell Anti-Tumor Response

Harnessing the IL-21-BATF Pathway in the CD8<sup>+</sup> T Cell Anti-Tumor Response

In cancer, CD8<sup>+</sup> T cells enter a dysfunctional state which prevents them from effectively targeting and killing tumor cells. Tumor-infiltrating CD8<sup>+</sup> T cells consist of a heterogeneous population of memory-like progenitor, effector, and terminally exhauste...

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Bibliographic Details
Main Authors:	Paytsar Topchyan, Gang Xin, Yao Chen, Shikan Zheng, Robert Burns, Jian Shen, Moujtaba Y. Kasmani, Matthew Kudek, Na Yang, Weiguo Cui
Format:	Article
Language:	English
Published:	MDPI AG 2021-03-01
Series:	Cancers
Subjects:	BATF IL-21 CD8 T cells CD4 T cells adoptive cell therapy cancer immunotherapy
Online Access:	https://www.mdpi.com/2072-6694/13/6/1263

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