Early changes in myocyte contractility and cardiac function in streptozotocin-induced type 1 diabetes in rats.

Diabetes can elicit direct deleterious effects on the myocardium, independent of coronary artery disease or hypertension. These cardiac disturbances are termed diabetic cardiomyopathy showing increased risk of heart failure with or without reduced ejection fraction. Presently, there is no specific t...

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Bibliographic Details
Main Authors: Gustavo S Marchini, Ismar N Cestari, Vera M C Salemi, Maria Claudia Irigoyen, Alexandre Arnold, Adélia Kakoi, Camila Rocon, Vera D Aiello, Idágene A Cestari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0237305