Computational Assessment of Bacterial Protein Structures Indicates a Selection Against Aggregation

Computational Assessment of Bacterial Protein Structures Indicates a Selection Against Aggregation

The aggregation of proteins compromises cell fitness, either because it titrates functional proteins into non-productive inclusions or because it results in the formation of toxic assemblies. Accordingly, computational proteome-wide analyses suggest that prevention of aggregation upon misfolding pla...

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Bibliographic Details
Main Authors: Anita Carija, Francisca Pinheiro, Valentin Iglesias, Salvador Ventura
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
protein aggregation
protein structure
protein function
cell proteostasis
<i>Escherichia coli</i>
Online Access:https://www.mdpi.com/2073-4409/8/8/856

Internet

https://www.mdpi.com/2073-4409/8/8/856

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