Alterations in the Expression of IFN Lambda, IFN Gamma and Toll-like Receptors in Severe COVID-19 Patients

Alterations in the Expression of IFN Lambda, IFN Gamma and Toll-like Receptors in Severe COVID-19 Patients

Contradictory results have been reported regarding interferon (IFN) lambda (λ1–3) and IFN gamma (γ) production in COVID-19 patients. To gain insight into the roles played by these IFNs in SARS-CoV-2 infection, IFNλ1–3 and IFNγ mRNA expression was evaluated in peripheral blood mononuclear cells (PBMC...

Full description

Bibliographic Details
Main Authors: Leonardo Sorrentino, Matteo Fracella, Federica Frasca, Alessandra D’Auria, Letizia Santinelli, Luca Maddaloni, Ginevra Bugani, Camilla Bitossi, Massimo Gentile, Giancarlo Ceccarelli, Ombretta Turriziani, Claudio Maria Mastroianni, Guido Antonelli, Gabriella d’Ettorre, Alessandra Pierangeli, Carolina Scagnolari
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Microorganisms
Subjects:
interferon
COVID-19
immunology
Online Access:https://www.mdpi.com/2076-2607/11/3/689

Internet

https://www.mdpi.com/2076-2607/11/3/689

Similar Items