Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease

Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease

A mis-metabolism of transition metals (i.e., copper, iron, and zinc) in the brain has been recognised as a precursor event for aggregation of Amyloid-β plaques, a pathological hallmark of Alzheimer’s disease (AD). However, imaging cerebral transition metals in vivo can be extremely challenging. As t...

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Bibliographic Details
Main Authors: Seyed Mostafa Hosseinpour Mashkani, David P. Bishop, Newsha Raoufi-Rad, Paul A. Adlard, Olga Shimoni, S. Mojtaba Golzan
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
Alzheimer’s disease
retina
transition metals
laser ablation inductively coupled plasma-mass spectrometry
Online Access:https://www.mdpi.com/2073-4409/12/8/1144

Internet

https://www.mdpi.com/2073-4409/12/8/1144

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