Integrin-Dependent Transient Density Increase in Detergent-Resistant Membrane Rafts in Platelets Activated by Thrombin

Integrin-Dependent Transient Density Increase in Detergent-Resistant Membrane Rafts in Platelets Activated by Thrombin

Platelet lipid rafts are critical membrane domains for adhesion, aggregation, and clot retraction. Lipid rafts are isolated as a detergent-resistant membrane fraction via sucrose density gradient centrifugation. The platelet detergent-resistant membrane shifted to a higher density on the sucrose den...

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Bibliographic Details
Main Authors: Keisuke Komatsuya, Masaki Ishikawa, Norihito Kikuchi, Tetsuya Hirabayashi, Ryo Taguchi, Naomasa Yamamoto, Morio Arai, Kohji Kasahara
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomedicines
Subjects:
lipid rafts
detergent-resistant membrane
sucrose density gradient
phosphatidylserine
platelets
clot retraction
Online Access:https://www.mdpi.com/2227-9059/12/1/69

Internet

https://www.mdpi.com/2227-9059/12/1/69

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