Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients

Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients

<p/> <p>Background</p> <p>Increased synthesis of neopterin and degradation of tryptophan to kynurenine, measured as kynurenine/tryptophan ratio (kyn/trp ratio), are considered <it>in vitro </it>markers of interferon beta-1a (IFNβ-1a) activity. The aim of the study...

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Bibliographic Details
Main Authors: Sessa Edoardo, Solda' Annalisa, Locatelli Laura, Fantozzi Roberta, Picconi Orietta, De Luca Giovanna, Bellantonio Paolo, Amato Mariapia, Bramanti Placido, Lugaresi Alessandra, Durastanti Valentina, Totaro Rocco, Marino Silvia, Zipoli Valentina, Zorzon Marino, Millefiorini Enrico
Format: Article
Language:English
Published: BMC 2011-04-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/42

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http://www.translational-medicine.com/content/9/1/42

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