The Antidepressant Paroxetine Reduces the Cardiac Sodium Current

The Antidepressant Paroxetine Reduces the Cardiac Sodium Current

A considerable amount of literature has been published on antidepressants and cardiac ion channel dysfunction. The antidepressant paroxetine has been associated with Brugada syndrome and long QT syndrome, albeit on the basis of conflicting findings. The cardiac voltage-gated sodium channel (Na<su...

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Bibliographic Details
Main Authors: Ingmar S. Plijter, Arie O. Verkerk, Ronald Wilders
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
antidepressant drugs
Na<sub>V</sub>1.5 channels
sodium current
action potential
cellular electrophysiology
patch clamp recordings
Online Access:https://www.mdpi.com/1422-0067/24/3/1904

Internet

https://www.mdpi.com/1422-0067/24/3/1904

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