Immunogenicity and safety of RAZI recombinant spike protein vaccine (RCP) as a booster dose after priming with BBIBP-CorV: a parallel two groups, randomized, double blind trial

Immunogenicity and safety of RAZI recombinant spike protein vaccine (RCP) as a booster dose after priming with BBIBP-CorV: a parallel two groups, randomized, double blind trial

Abstract Background The immunity induced by primary vaccination is effective against COVID-19; however, booster vaccines are needed to maintain vaccine-induced immunity and improve protection against emerging variants. Heterologous boosting is believed to result in more robust immune responses. This...

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Bibliographic Details
Main Authors: Saeed Erfanpoor, Seyed Reza Banihashemi, Ladan Mokhbaeralsafa, Saeed Kalantari, Ali Es-haghi, Mojtaba Nofeli, Ali Rezaei Mokarram, Fariba Sadeghi, Monireh Hajimoradi, Seyad Hossein Razaz, Maryam Taghdiri, Mohsen Lotfi, Akbar Khorasani, Akram Ansarifar, Safdar Masoumi, Arash Mohazzab, Sara Filsoof, Vahideh Mohseni, Masoumeh Shahsavan, Niloufar Gharavi, Seyed Amin Setarehdan, Mohammad Hasan Rabiee, Mohammad Hossein Fallah Mehrabadi, Masoud Solaymani-Dodaran
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Medicine
Subjects:
SARS-CoV-2
Recombinant Vaccine
Booster dose
Heterologous boosting
Online Access:https://doi.org/10.1186/s12916-024-03295-1

Internet

https://doi.org/10.1186/s12916-024-03295-1

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