Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines.

Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines.

Recent clinical trials investigating receptor tyrosine kinase (RTK) inhibitors showed a limited clinical response in medulloblastoma. The present study investigated the role of micro-environmental growth factors expressed in the brain, such as HGF and EGF, in relation to the effects of hepatocyte gr...

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Bibliographic Details
Main Authors: Walderik W Zomerman, Sabine L A Plasschaert, Sander H Diks, Harm-Jan Lourens, Tiny Meeuwsen-de Boer, Eelco W Hoving, Wilfred F A den Dunnen, Eveline S J M de Bont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4619778?pdf=render

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http://europepmc.org/articles/PMC4619778?pdf=render

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