Decidualized human decidual stromal cells inhibit chemotaxis of activated T cells: a potential mechanism of maternal-fetal immune tolerance

Decidualized human decidual stromal cells inhibit chemotaxis of activated T cells: a potential mechanism of maternal-fetal immune tolerance

BackgroundNumerous lines of evidence confirm that decidual stromal cells (DSCs) play a key role in maternal–fetal immune tolerance. Under the influence of progesterone and other hormones, the DSCs go through a process of differentiation (decidualization) during normal pregnancy. In mice, DSCs inhibi...

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Bibliographic Details
Main Authors: Tatiana Llorca, Maria Jose Ruiz-Magaña, Rocio Martinez-Aguilar, Olga María García-Valdeavero, Lucia Rodríguez-Doña, Ana Clara Abadia-Molina, Carmen Ruiz-Ruiz, Enrique G. Olivares
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
chemotaxis
decidual stromal cells
decidualization
Th1 cells
Tc cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1223539/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1223539/full

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