Global effects of identity and aging on the human sperm methylome

Abstract Background As the average age of fatherhood increases worldwide, so too does the need for understanding effects of aging in male germline cells. Molecular change, including epigenomic alterations, may impact offspring. Age-associated change to DNA cytosine methylation in the cytosine–guanin...

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Bibliographic Details
Main Authors: Guilherme de Sena Brandine, Kenneth I. Aston, Timothy G. Jenkins, Andrew D. Smith
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Clinical Epigenetics
Online Access:https://doi.org/10.1186/s13148-023-01541-6