Synthesis, Bioactivity, Pharmacokinetic and Biomimetic Properties of Multi-Substituted Coumarin Derivatives

Synthesis, Bioactivity, Pharmacokinetic and Biomimetic Properties of Multi-Substituted Coumarin Derivatives

A series of novel multi-substituted coumarin derivatives were synthesized, spectroscopically characterized, and evaluated for their antioxidant activity, soybean lipoxygenase (LOX) inhibitory ability, their influence on cell viability in immortalized human keratinocytes (HaCaT), and cytotoxicity in...

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Bibliographic Details
Main Authors: Annita Katopodi, Evangelia Tsotsou, Triantafylia Iliou, Georgia-Eirini Deligiannidou, Eleni Pontiki, Christos Kontogiorgis, Fotios Tsopelas, Anastasia Detsi
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
coumarins
antioxidant activity
lipoxygenase inhibition
cytotoxicity
molecular docking
biomimetic chromatography
Online Access:https://www.mdpi.com/1420-3049/26/19/5999

Internet

https://www.mdpi.com/1420-3049/26/19/5999

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