Identification of novel MCM2 inhibitors from Catharanthus roseus by pharmacoinformatics, molecular docking and molecular dynamics simulation-based evaluation
Nearly all living cells undergo DNA replication in order to duplicate their genome; this multi-step biological process is tightly regulated by different cellular machineries and numerous multi-protein complexes. MCM2 (Minichromosome maintenance protein 2) is a key player in this game and its express...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-01-01
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| Series: | Informatics in Medicine Unlocked |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S235291482300093X |