Sex-Specific Linear Polyubiquitination Is a Critical Regulator of Contextual Fear Memory Formation

Strong evidence supports that protein ubiquitination is a critical regulator of fear memory formation. However, as this work has focused on protein degradation, it is currently unknown whether polyubiquitin modifications that are independent of the proteasome are involved in learning-dependent synap...

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Bibliographic Details
Main Authors: Madeline Musaus, Kayla Farrell, Shaghayegh Navabpour, W. Keith Ray, Richard F. Helm, Timothy J. Jarome
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.709392/full