Rho GTPases and their downstream effectors in megakaryocyte biology

Rho GTPases and their downstream effectors in megakaryocyte biology

Megakaryocytes differentiate from hematopoietic stem cells in the bone marrow. The transition of megakaryocytes to platelets is a complex process. Thereby, megakaryocytes extend proplatelets into sinusoidal blood vessels, where the proplatelets undergo fission to release platelets. Defects in platel...

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Bibliographic Details
Main Authors: Irina Pleines, Deya Cherpokova, Markus Bender
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Platelets
Subjects:
cdc42
cytoskeleton
megakaryocyte
platelet
rac1
rhoa
rho gtpases
Online Access:http://dx.doi.org/10.1080/09537104.2018.1478071

Internet

http://dx.doi.org/10.1080/09537104.2018.1478071

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