An axon-specific expression of HCN channels catalyzes fast action potential signaling in GABAergic interneurons

The precise subcellular location of ion channels is a key determinant of their functions. Here, subcellular patch-clamp recordings demonstrate that an axon-specific expression of HCN channels facilitates the initiation and propagation of action potentials in parvalbumin-expressing basket cells.

Bibliographic Details
Main Authors: Fabian C. Roth, Hua Hu
Format: Article
Language:English
Published: Nature Portfolio 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15791-y