Metabolic engineering for efficient supply of acetyl-CoA from different carbon sources in Escherichia coli

Metabolic engineering for efficient supply of acetyl-CoA from different carbon sources in Escherichia coli

Abstract Background Acetyl-CoA is an important metabolic intermediate and serves as an acetylation precursor for the biosynthesis of various value-added acetyl-chemicals. Acetyl-CoA can be produced from glucose, acetate, or fatty acids via metabolic pathways in Escherichia coli. Although glucose is...

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Bibliographic Details
Main Authors: Shasha Zhang, Wei Yang, Hao Chen, Bo Liu, Baixue Lin, Yong Tao
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Microbial Cell Factories
Subjects:
N-Acetylglutamate
Acetyl-CoA
Glucose
Acetate
Fatty acid
Online Access:http://link.springer.com/article/10.1186/s12934-019-1177-y

Internet

http://link.springer.com/article/10.1186/s12934-019-1177-y

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