SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability

Summary: During genome duplication, replication forks (RFs) can be stalled by different obstacles or by depletion of replication factors or nucleotides. A limited number of histone post-translational modifications at stalled RFs are involved in RF protection and restart. Provided the recent observat...

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Bibliographic Details
Main Authors: Sergio Muñoz, Sonia Barroso, Nibal Badra-Fajardo, José Javier Marqueta-Gracia, María L. García-Rubio, Patricia Ubieto-Capella, Juan Méndez, Andrés Aguilera
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724001062