Upregulation of miR-501-5p activates the wnt/β-catenin signaling pathway and enhances stem cell-like phenotype in gastric cancer

Abstract Background miRNAs are critical post-transcriptional regulators of gene expression and key mediators of tumourigenesis. miR-501-5p is newly identified to be involved in the tumor progression, but its biological role and mechanism remain largely unknown. This study is aimed to study the role...

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Bibliographic Details
Main Authors: Dongmei Fan, Baoqi Ren, Xiaojun Yang, Jia Liu, Zhengzheng Zhang
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-016-0432-x