Metallopeptidades 2 and 9 genes epigenetically modulate equine endometrial fibrosis

Metallopeptidades 2 and 9 genes epigenetically modulate equine endometrial fibrosis

Endometrium type I (COL1) and III (COL3) collagen accumulation, periglandular fibrosis and mare infertility characterize endometrosis. Metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) are involved in collagen turnover. Since epigenetic changes may co...

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Bibliographic Details
Main Authors: Joana Alpoim-Moreira, Carina Fernandes, Jorge Pimenta, Miguel Bliebernicht, Maria Rosa Rebordão, Pedro Castelo-Branco, Anna Szóstek-Mioduchowska, Dariusz J. Skarzynski, Graça Ferreira-Dias
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Veterinary Science
Subjects:
endometrial fibrosis
mare
collagen
epigenetics
DNMT
MMP
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.970003/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2022.970003/full

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