Metallopeptidades 2 and 9 genes epigenetically modulate equine endometrial fibrosis

Metallopeptidades 2 and 9 genes epigenetically modulate equine endometrial fibrosis

Endometrium type I (COL1) and III (COL3) collagen accumulation, periglandular fibrosis and mare infertility characterize endometrosis. Metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2) are involved in collagen turnover. Since epigenetic changes may co...

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Bibliographic Details
Main Authors:	Joana Alpoim-Moreira, Carina Fernandes, Jorge Pimenta, Miguel Bliebernicht, Maria Rosa Rebordão, Pedro Castelo-Branco, Anna Szóstek-Mioduchowska, Dariusz J. Skarzynski, Graça Ferreira-Dias
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Veterinary Science
Subjects:	endometrial fibrosis mare collagen epigenetics DNMT MMP
Online Access:	https://www.frontiersin.org/articles/10.3389/fvets.2022.970003/full

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