miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation

miR-351 promotes atherosclerosis in diabetes by inhibiting the ITGB3/PIK3R1/Akt pathway and induces endothelial cell injury and lipid accumulation

Abstract Background The miR-351 gene is significantly upregulated in diabetic mice with atherosclerosis. However, the mechanism by which its presence is important for the overall disease has not been elucidated. Therefore, this study will investigate the mechanism of miR-351 in the process of diabet...

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Bibliographic Details
Main Authors: Hong Li, Dan Song, Qihui Liu, Linlin Li, Xiaoshi Sun, Jiamei Guo, Dianlian Li, Ping Li
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Molecular Medicine
Subjects:
Atherosclerosis
Diabetes mellitus
miR-351
ITGB3
Aortic endothelial cells
Online Access:https://doi.org/10.1186/s10020-022-00547-9

Internet

https://doi.org/10.1186/s10020-022-00547-9

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