DNA Damage Regulates the Functions of the RNA Binding Protein Sam68 through ATM-Dependent Phosphorylation

DNA Damage Regulates the Functions of the RNA Binding Protein Sam68 through ATM-Dependent Phosphorylation

Cancer cells frequently exhibit dysregulation of the DNA damage response (DDR), genomic instability, and altered RNA metabolism. Recent genome-wide studies have strongly suggested an interaction between the pathways involved in the cellular response to DDR and in the regulation of RNA metabolism, bu...

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Bibliographic Details
Main Authors: Venturina Stagni, Silvia Orecchia, Luca Mignini, Sara Beji, Ambra Antonioni, Cinzia Caggiano, Daniela Barilà, Pamela Bielli, Claudio Sette
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cancers
Subjects:
DNA damage
ATM kinase
Sam68
alternative splicing
alternative polyadenylation
Online Access:https://www.mdpi.com/2072-6694/14/16/3847

Internet

https://www.mdpi.com/2072-6694/14/16/3847

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