Microinjection of angiotensin II into zebrafish embryos induces transient dilation and elastin disruption of the dorsal aorta

Microinjection of angiotensin II into zebrafish embryos induces transient dilation and elastin disruption of the dorsal aorta

Abstract The effects of angiotensin II (AngII) on blood vessel development and remodeling have been extensively investigated in mice and humans. However, its action on the vessels in the zebrafish remains largely unknown. To investigate whether AngII affects vascular morphology in vivo, we administe...

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Bibliographic Details
Main Authors: Shota Tanifuji, Keiko Uchida, Genri Kawahara, Takashi Nakamura, Saki Iida, Yukiko K. Hayashi, Utako Yokoyama
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Physiological Reports
Subjects:
angiotensin II
blood vessels
development
elastic fibers
zebrafish
Online Access:https://doi.org/10.14814/phy2.70259

Internet

https://doi.org/10.14814/phy2.70259

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