Drosophila melanogaster retrotransposon and inverted repeat-derived endogenous siRNAs are differentially processed in distinct cellular locations

Drosophila melanogaster retrotransposon and inverted repeat-derived endogenous siRNAs are differentially processed in distinct cellular locations

Abstract Background Endogenous small interfering (esi)RNAs repress mRNA levels and retrotransposon mobility in Drosophila somatic cells by poorly understood mechanisms. 21 nucleotide esiRNAs are primarily generated from retrotransposons and two inverted repeat (hairpin) loci in Drosophila culture ce...

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Bibliographic Details
Main Authors: Andrew W. Harrington, Michael R. McKain, Daniel Michalski, Kaylyn M. Bauer, Joshua M. Daugherty, Mindy Steiniger
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Genomics
Subjects:
Dicer2
mRNA 3’ end processing
Endogenous small interfering RNA biogenesis
Core cleavage complex
Symplekin
CPSF73
Online Access:http://link.springer.com/article/10.1186/s12864-017-3692-8

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http://link.springer.com/article/10.1186/s12864-017-3692-8

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