Enterovirus RNA in peripheral blood may be associated with the variants of rs1990760, a common type 1 diabetes associated polymorphism in IFIH1.

Enterovirus RNA in peripheral blood may be associated with the variants of rs1990760, a common type 1 diabetes associated polymorphism in IFIH1.

Polymorphisms in the IFIH1 (common rs1990760 and four rare rs35667974, rs35337543, rs35744605, rs35732034) have been convincingly associated with type 1 diabetes. The encoded protein (interferon-induced helicase C domain-containing protein 1) senses double-stranded RNA during replication of Picornav...

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Bibliographic Details
Main Authors: Ondrej Cinek, German Tapia, Elisabet Witsø, Lenka Kramna, Katerina Holkova, Trond Rasmussen, Lars C Stene, Kjersti S Rønningen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492349?pdf=render

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http://europepmc.org/articles/PMC3492349?pdf=render

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