Computational modeling reveals optimal strategy for kinase transport by microtubules to nerve terminals.

Intracellular transport of proteins by motors along cytoskeletal filaments is crucial to the proper functioning of many eukaryotic cells. Since most proteins are synthesized at the cell body, mechanisms are required to deliver them to the growing periphery. In this article, we use computational mode...

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Bibliographic Details
Main Authors: Yen Ling Koon, Cheng Gee Koh, Keng-Hwee Chiam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0092437&type=printable