SirT7-mediated transcription of fascin in hyperglycemic glomerular endothelial cells contributes to EndMT in diabetic nephropathy

SirT7-mediated transcription of fascin in hyperglycemic glomerular endothelial cells contributes to EndMT in diabetic nephropathy

Diabetic nephropathy (DN) is the main cause of end-stage renal disease worldwide. It is reported that the endothelial-to-mesenchymal transition (EndMT) in glomerular endothelial cells plays an important role in DN. As a specific form of epithelial-to-mesenchymal transition, EndMT may involve common...

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Bibliographic Details
Main Authors: Wu Mengchen, Hao Yingxiang, Wu Xinwan, Zhu Minmin, Chen Xiangyuan, Qi Jie, Yu Zhuang, Xu Hongjiao
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-03-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
endothelial-to-mesenchymal transition
diabetic nephropathy
glomerular endothelial cell, SirT7
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024002

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https://www.sciengine.com/doi/10.3724/abbs.2024002

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