Synapsin autoantibodies during pregnancy are associated with fetal abnormalities

Synapsin autoantibodies during pregnancy are associated with fetal abnormalities

Anti-neuronal autoantibodies can be transplacentally transferred during pregnancy and may cause detrimental effects on fetal development. It is unclear whether autoantibodies against synapsin-I, one of the most abundant synaptic proteins, are associated with developmental abnormalities in humans. We...

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Bibliographic Details
Main Authors: Isabel Bünger, Ivan Talucci, Jakob Kreye, Markus Höltje, Konstantin L. Makridis, Helle Foverskov Rasmussen, Scott van Hoof, César Cordero-Gomez, Tim Ullrich, Eva Sedlin, Kai Oliver Kreissner, Christian Hoffmann, Dragomir Milovanovic, Paul Turko, Friedemann Paul, Jessica Meckies, Stefan Verlohren, Wolfgang Henrich, Rabih Chaoui, Hans Michael Maric, Angela M. Kaindl, Harald Prüss
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Synapsin-I
Antineuronal autoantibodies
Transplacental transfer
Maternofetal autoimmunity
Growth retardation
Peptide microarray
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354623000923

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http://www.sciencedirect.com/science/article/pii/S2666354623000923

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