Endothelial KLF11 is a novel protector against diabetic atherosclerosis

Endothelial KLF11 is a novel protector against diabetic atherosclerosis

Abstract Background Atherosclerotic cardiovascular diseases remain the leading cause of mortality in diabetic patients, with endothelial cell (EC) dysfunction serving as the initiating step of atherosclerosis, which is exacerbated in diabetes. Krüppel-like factor 11 (KLF11), known for its missense m...

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Bibliographic Details
Main Authors: Guizhen Zhao, Yang Zhao, Wenying Liang, Haocheng Lu, Hongyu Liu, Yongjie Deng, Tianqing Zhu, Yanhong Guo, Lin Chang, Minerva T. Garcia-Barrio, Y. Eugene Chen, Jifeng Zhang
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Cardiovascular Diabetology
Subjects:
Atherosclerosis
Diabetes
Endothelial cell
KLF11
Endothelial-to-mesenchymal transition (EndMT)
Online Access:https://doi.org/10.1186/s12933-024-02473-y

Internet

https://doi.org/10.1186/s12933-024-02473-y

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