Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE)

The authors demonstrate a real-time, non-invasive, far-field optical probe to monitor particle size distribution in pharmaceutical manufacturing. It characterizes the speckle scattered from the surface using machine learning weaved into optical physics.

Bibliographic Details
Main Authors: Qihang Zhang, Janaka C. Gamekkanda, Ajinkya Pandit, Wenlong Tang, Charles Papageorgiou, Chris Mitchell, Yihui Yang, Michael Schwaerzler, Tolutola Oyetunde, Richard D. Braatz, Allan S. Myerson, George Barbastathis
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36816-2