Betulinic Acid Attenuates Oxidative Stress in the Thymus Induced by Acute Exposure to T-2 Toxin via Regulation of the MAPK/Nrf2 Signaling Pathway

Betulinic Acid Attenuates Oxidative Stress in the Thymus Induced by Acute Exposure to T-2 Toxin via Regulation of the MAPK/Nrf2 Signaling Pathway

T-2 toxin, the most toxic of the trichothecenes, is widely found in grains and feeds, and its intake poses serious risks to the health of humans and animals. An important cytotoxicity mechanism of T-2 toxin is the production of excess free radicals, which in turn leads to oxidative stress. Betulinic...

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Bibliographic Details
Main Authors: Lijuan Zhu, Xianglian Yi, Chaoyang Ma, Chenxi Luo, Li Kong, Xing Lin, Xinyu Gao, Zhihang Yuan, Lixin Wen, Rongfang Li, Jing Wu, Jine Yi
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Toxins
Subjects:
T-2 toxin
thymus
betulinic acid
MAPK/Nrf2
oxidative stress
Online Access:https://www.mdpi.com/2072-6651/12/9/540

Internet

https://www.mdpi.com/2072-6651/12/9/540

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